WDR62 Antibody (PACO31080)
- SKU:
- PACO31080
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | WDR62 Antibody (PACO31080) |
Antibody SKU: | PACO31080 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human WD repeat-containing protein 62 protein (889-1188AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human bladder cancer using PACO31080 at dilution of 1:100. |
Background: | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. |
Synonyms: | WD repeat-containing protein 62, WDR62, C19orf14 |
UniProt Protein Function: | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (PubMed:20890278, PubMed:20729831). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). |
UniProt Protein Details: | |
NCBI Summary: | This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] |
UniProt Code: | O43379 |
NCBI GenInfo Identifier: | 145580608 |
NCBI Gene ID: | 284403 |
NCBI Accession: | NP_001077430.1 |
UniProt Secondary Accession: | O43379,Q63HP9, Q659D7, Q8NBF7, Q96AD9 |
UniProt Related Accession: | O43379 |
Molecular Weight: | 166,511 Da |
NCBI Full Name: | WD repeat-containing protein 62 isoform 1 |
NCBI Synonym Full Names: | WD repeat domain 62 |
NCBI Official Symbol: | WDR62 |
NCBI Official Synonym Symbols: | MCPH2; C19orf14 |
NCBI Protein Information: | WD repeat-containing protein 62 |
UniProt Protein Name: | WD repeat-containing protein 62 |
UniProt Synonym Protein Names: | |
Protein Family: | WD repeat-containing protein |
UniProt Gene Name: | WDR62 |
UniProt Entry Name: | WDR62_HUMAN |