Anti-VGF 항체의 (PACO20853)

Antibody Name:	VGF Antibody (PACO20853)
Antibody SKU:	PACO20853
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human, Rat
Immunogen:	Synthetic peptide of human VGF

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20853(VGF Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20853(VGF Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.

Synonyms:

VGF nerve growth factor inducible

UniProt Protein Function:	VGF: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.
UniProt Protein Details:	Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: extracellular space; transport vesicle; cytoplasmic vesicle Molecular Function:neuropeptide hormone activity; growth factor activity Biological Process: response to dietary excess; generation of precursor metabolites and energy; response to cAMP; ovarian follicle development; insulin secretion; sexual reproduction; defense response to bacterium; response to cold; glucose homeostasis; response to insulin stimulus
NCBI Summary:	This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
UniProt Code:	O15240
NCBI GenInfo Identifier:	206729943
NCBI Gene ID:	7425
NCBI Accession:	O15240.2
UniProt Secondary Accession:	O15240,Q9UDW8,
UniProt Related Accession:	O15240
Molecular Weight:	67,258 Da
NCBI Full Name:	Neurosecretory protein VGF
NCBI Synonym Full Names:	VGF nerve growth factor inducible
NCBI Official Symbol:	VGF
NCBI Protein Information:	neurosecretory protein VGF; neuro-endocrine specific protein VGF
UniProt Protein Name:	Neurosecretory protein VGF
Protein Family:	Neurosecretory protein
UniProt Gene Name:	VGF
UniProt Entry Name:	VGF_HUMAN

Antibodies	ELISA Kits
Anti-VGF Antibody (CAB14795)	Human VGF / Nerve Growth Factor Inducible ELISA Kit
VGF Antibody (PACO01996)	Human Neurosecretory protein VGF (VGF) ELISA Kit
VGF Antibody (PACO05296)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)