TREH Antibody (PACO58957)
- SKU:
- PACO58957
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | TREH Antibody (PACO58957) |
| Antibody SKU: | PACO58957 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Trehalase protein (373-507AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO58957 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose. |
| Synonyms: | Trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase), TREH, TREA |
| UniProt Protein Function: | TREH: Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose. Deficiency of TREH results in isolated trehalose intolerance that causes gastrointestinal symptoms after ingestion of edible mushrooms. Belongs to the glycosyl hydrolase 37 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.2.1.28; Membrane protein, GPI anchor; Carbohydrate Metabolism - starch and sucrose; Hydrolase Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: anchored to plasma membrane; plasma membrane Molecular Function:alpha,alpha-trehalase activity Biological Process: polysaccharide digestion; organ morphogenesis; trehalose catabolic process; trehalose metabolic process; carbohydrate metabolic process; pathogenesis Disease: Trehalase Deficiency |
| NCBI Summary: | This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| UniProt Code: | O43280 |
| NCBI GenInfo Identifier: | 116284412 |
| NCBI Gene ID: | 11181 |
| NCBI Accession: | NP_009111.2 |
| UniProt Secondary Accession: | O43280,Q32MB9, Q53FY8, |
| UniProt Related Accession: | O43280 |
| Molecular Weight: | 62,941 Da |
| NCBI Full Name: | trehalase isoform 1 |
| NCBI Synonym Full Names: | trehalase (brush-border membrane glycoprotein) |
| NCBI Official Symbol: | TREH |
| NCBI Official Synonym Symbols: | TRE; TREA |
| NCBI Protein Information: | trehalase; alpha,alpha-trehalose glucohydrolase |
| UniProt Protein Name: | Trehalase |
| UniProt Synonym Protein Names: | Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase |
| Protein Family: | Trehalase |
| UniProt Gene Name: | TREH |
| UniProt Entry Name: | TREA_HUMAN |
| Antibodies |
| Anti-TREH Antibody (CAB15397) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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