TPO Antibody (PACO33204)
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주문- SKU:
- PACO33204
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TPO Antibody (PACO33204) |
Antibody SKU: | PACO33204 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Thyroid peroxidase protein (19-846AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO33204 at dilution of 1:100. |
Background: | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4. |
Synonyms: | Thyroid peroxidase (TPO) (EC 1.11.1.8), TPO |
UniProt Protein Function: | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4. |
NCBI Summary: | This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] |
UniProt Code: | P07202 |
NCBI GenInfo Identifier: | 160281455 |
NCBI Gene ID: | 7173 |
NCBI Accession: | P07202.4 |
UniProt Secondary Accession: | P07202,P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96 Q8NF97, Q8TCI9, |
UniProt Related Accession: | P07202 |
Molecular Weight: | 96,699 Da |
NCBI Full Name: | Thyroid peroxidase |
NCBI Synonym Full Names: | thyroid peroxidase |
NCBI Official Symbol: | TPO |
NCBI Official Synonym Symbols: | MSA; TPX; TDH2A |
NCBI Protein Information: | thyroid peroxidase |
UniProt Protein Name: | Thyroid peroxidase |
Protein Family: | Thyroid peroxidase |
UniProt Gene Name: | TPO |