Tbx15 Antibody (PACO30294)
- SKU:
- PACO30294
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Tbx15 Antibody (PACO30294) |
| Antibody SKU: | PACO30294 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse T-box transcription factor TBX15 protein (1-120AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes. |
| Synonyms: | T-box transcription factor TBX15 (T-box protein 15) (MmTBx8) (T-box transcription factor TBX14) (T-box protein 14), Tbx15, Tbx14 Tbx8 |
| UniProt Protein Function: | TBX15: Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes. Defects in TBX15 are the cause of Cousin syndrome (COUSS); also known as craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature. Cousin syndrome is defined as pelviscapular dysplasia with epiphyseal abnormalities, congenital dwarfism and facial dysmorphy (frontal bossing, hypertelorism, narrow palpebral fissures, deep set globes, strabismus, low-set posteriory rotated and unusually formed external ears, dysplasia of conchae, small chin, short neck with redundant skin folds, and a low hairline). Intelligence may vary from normal to moderately impaired. Radiographic features comprise aplasia of the body of the scapula, hypoplasia of the iliac bone, humeroradial synosthosis, dislocation of the femoral heads, and moderate brachydactyly. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-bindingCellular Component: nucleusMolecular Function: DNA binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activityBiological Process: embryonic cranial skeleton morphogenesis; embryonic skeletal morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O70306 |
| NCBI GenInfo Identifier: | 124286802 |
| NCBI Gene ID: | 21384 |
| NCBI Accession: | NP_033349.2 |
| UniProt Secondary Accession: | O70306,O54840, Q5GBG1 |
| UniProt Related Accession: | O70306 |
| Molecular Weight: | 65,802 Da |
| NCBI Full Name: | T-box transcription factor TBX15 |
| NCBI Synonym Full Names: | T-box 15 |
| NCBI Official Symbol: | Tbx15 |
| NCBI Official Synonym Symbols: | de; Tbx8; Tbx14 |
| NCBI Protein Information: | T-box transcription factor TBX15 |
| UniProt Protein Name: | T-box transcription factor TBX15 |
| UniProt Synonym Protein Names: | MmTBx8; T-box transcription factor TBX14; T-box protein 14 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | Tbx15 |
| UniProt Entry Name: | TBX15_MOUSE |
Related Products
Human TBX15 (T-box transcription factor TBX15) ELISA Kit (HUFI06179)
Mouse TBX15 (T-box transcription factor TBX15) ELISA Kit (MOFI01404)
