TAF1A Antibody (PACO05664)

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SKU:
PACO05664
Product type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Application:
WB
Application:
IHC
Antibody type:
Polyclonal
Conjugation:
Unconjugated
Frequently bought together:

Description

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Antibody Name:TAF1A Antibody (PACO05664)
Antibody SKU:PACO05664
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Rat
Immunogen:Synthesized peptide derived from the Internal region of human TAF I p48.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; RNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1;
UniProt Protein Function:TAF1A: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q42

Cellular Component: intracellular membrane-bound organelle; microtubule cytoskeleton; nucleoplasm; nucleus; RNA polymerase I transcription factor complex

Molecular Function:protein binding

Biological Process: positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase I promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter

NCBI Summary:This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011]
UniProt Code:Q15573
NCBI GenInfo Identifier:74739864
NCBI Gene ID:9015
NCBI Accession:Q15573.1
UniProt Secondary Accession:Q15573,Q9NWA1, B2RDZ8, D3DTB7,
UniProt Related Accession:Q15573
Molecular Weight:39,615 Da
NCBI Full Name:TATA box-binding protein-associated factor RNA polymerase I subunit A
NCBI Synonym Full Names:TATA-box binding protein associated factor, RNA polymerase I subunit A
NCBI Official Symbol:TAF1A  
NCBI Official Synonym Symbols:SL1; RAFI48; TAFI48; MGC:17061  
NCBI Protein Information:TATA box-binding protein-associated factor RNA polymerase I subunit A
UniProt Protein Name:TATA box-binding protein-associated factor RNA polymerase I subunit A
UniProt Synonym Protein Names:RNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit A
Protein Family:TATA box-binding protein-associated factor
UniProt Gene Name:TAF1A  
UniProt Entry Name:TAF1A_HUMAN

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