SPON1 Antibody (PACO20597)
- SKU:
- PACO20597
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SPON1 Antibody (PACO20597) |
| Antibody SKU: | PACO20597 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human SPON1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Mouse brain tissue, Mouse lung tissue, Primary antibody: PACO20597(SPON1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20597(SPON1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | F-Spondin, also designated Spondin-1 or vascular smooth muscle growth-promoting factor, is a member of the subgroup of the Thrombospondin type 1 class molecules. F-Spondin is a secreted, extracellular matrix-attached protein which patterns axonal trajectories by promoting adhesion and outgrowth of commissural axons, in addition to inhibiting outgrowth of motor axons. |
| Synonyms: | spondin 1, extracellular matrix protein |
| UniProt Protein Function: | SPON1: Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS. Major factor for vascular smooth muscle cell. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11p15.2 Cellular Component: endoplasmic reticulum lumen; extracellular matrix; extracellular space Molecular Function:protein binding |
| UniProt Code: | Q9HCB6 |
| NCBI GenInfo Identifier: | 52783472 |
| NCBI Gene ID: | 10418 |
| NCBI Accession: | Q9HCB6.2 |
| UniProt Secondary Accession: | Q9HCB6,O94862, Q8NCD7, Q8WUR5, A8K6W5, |
| UniProt Related Accession: | Q9HCB6 |
| Molecular Weight: | 90,973 Da |
| NCBI Full Name: | Spondin-1 |
| NCBI Synonym Full Names: | spondin 1 |
| NCBI Official Symbol: | SPON1 |
| NCBI Official Synonym Symbols: | f-spondin; VSGP/F-spondin |
| NCBI Protein Information: | spondin-1 |
| UniProt Protein Name: | Spondin-1 |
| UniProt Synonym Protein Names: | F-spondin; Vascular smooth muscle cell growth-promoting factor |
| Protein Family: | Spondin |
| UniProt Gene Name: | SPON1 |
| UniProt Entry Name: | SPON1_HUMAN |
| Antibodies |
| Anti-SPON1 Antibody (CAB15130) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Anti-SPON1 Antibody (CAB15130)
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