SOX12 Transcription Factor Activity Assay
- SKU:
- TFAB00199
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- SOX12
- Reactivity:
- Human
- Mouse
Description
SOX12 Transcription Factor Activity Assay
The SOX12 Transcription Factor Activity Assay offered by Assay Genie is a cutting-edge tool for the precise measurement of SOX12 transcription factor activity in a variety of experimental samples. This assay boasts exceptional sensitivity and specificity, guaranteeing accurate and consistent results for a diverse array of research endeavors.SOX12 is a key transcription factor responsible for regulating gene expression and influencing cellular processes such as differentiation, development, and proliferation. Its role in various biological pathways makes it a valuable target for studying conditions such as cancer, developmental disorders, and neurological diseases.
By utilizing the SOX12 Transcription Factor Activity Assay, researchers can gain valuable insights into the intricate mechanisms underlying these conditions, paving the way for the development of innovative therapeutic strategies. Trust Assay Genie to provide you with a reliable and efficient solution for exploring the fascinating world of SOX12 transcription factor activity.
Product Name: | SOX12 Transcription Factor Activity Assay |
Product Code: | TFAB00199 |
Target: | SOX12 |
Reactivity: | Human, Mouse |
Sample Types: | Nuclear or cell lysates |
The Assay Genie SOX12 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
Assay Time: | 4.5 hours |
Detection Method: | Colorimetric 450 nm |
Size: | 12 x 8-Well Microstrips |
Storage: | 4°C for 6 months |
UniProt Protein Function: | Function: Binds to the sequence 5'-AACAAT-3' |
UniProt Protein Details: | By similarity. Subcellular location: Nucleus Ref.1. Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1 Sequence similarities: Contains 1 HMG box DNA-binding domain. Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201. |
NCBI Summary: | Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013] |
UniProt Code: | O15370 |
NCBI GenInfo Identifier: | 21264339 |
NCBI Gene ID: | 6666 |
NCBI Accession: | NP_008874 |
UniProt Related Accession: | O15370 |
Molecular Weight: | 34kDa |
NCBI Full Name: | transcription factor SOX-12 |
NCBI Synonym Full Names: | SRY-box 12 |
NCBI Official Symbol: | SOX12 |
NCBI Official Synonym Symbols: | SOX22 |
NCBI Protein Information: | transcription factor SOX-12 |
UniProt Protein Name: | Transcription factor SOX-12 |
UniProt Synonym Protein Names: | Protein SOX-22 |
Protein Family: | Transcription factor |
UniProt Gene Name: | SOX12 |
UniProt Entry Name: | SOX12_HUMAN |
Antibodies |
SOX12 Antibody (PACO05107) |