Serpinh1 Antibody (PACO29852)

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Description

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Product Code:

CAB13474

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

Product Code:

RPES4763

Product Code:

RPPB5238

Product Code:

CHEB0057

ELISA Type:

Sandwich

Product Code:

BOEB0145

ELISA Type:

Sandwich

Antibody Name:	Serpinh1 Antibody (PACO29852)
Antibody SKU:	PACO29852
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:	Mouse, Human
Immunogen:	Recombinant Mouse Serpin H1 protein (18-417AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Synonyms:	Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6), Serpinh1, Cbp1 Hsp47

UniProt Protein Function:	SERPINH1: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. Defects in SERPINH1 are the cause of osteogenesis imperfecta type 10 (OI10). A connective tissue disorder characterized by bone fragility, low bone mass, bowing of limbs due to multiple fractures, short limb dwarfism and blue sclerae. Belongs to the serpin family.Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartmentMolecular Function: serine-type endopeptidase inhibitor activity; collagen binding; protein binding; unfolded protein bindingBiological Process: collagen fibril organization; protein maturation; collagen biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	P19324
NCBI GenInfo Identifier:	161353504
NCBI Gene ID:	12406
NCBI Accession:	NP_001104513.1
UniProt Secondary Accession:	P19324,Q5U4D0
UniProt Related Accession:	P19324
Molecular Weight:
NCBI Full Name:	serpin H1
NCBI Synonym Full Names:	serine (or cysteine) peptidase inhibitor, clade H, member 1
NCBI Official Symbol:	Serpinh1
NCBI Official Synonym Symbols:	J6; Cbp1; Cbp2; gp46; Hsp47; BERF-1; Serpinh2
NCBI Protein Information:	serpin H1
UniProt Protein Name:	Serpin H1
UniProt Synonym Protein Names:	47 kDa heat shock protein; Collagen-binding protein; Colligin; Serine protease inhibitor J6
Protein Family:
UniProt Gene Name:	Serpinh1
UniProt Entry Name:	SERPH_MOUSE