SERPINB12 Antibody (PACO38190)
- SKU:
- PACO38190
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SERPINB12 Antibody (PACO38190) |
| Antibody SKU: | PACO38190 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Serpin B12 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO38190 diluted at 1:200 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of A549 cells with PACO38190 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO38190 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. |
| Synonyms: | Serpin B12, SERPINB12 |
| UniProt Protein Function: | SERPINB12: Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. Belongs to the serpin family. Ov-serpin subfamily.Protein type: InhibitorChromosomal Location of Human Ortholog: 18q21.33Cellular Component: cytoplasm; extracellular spaceMolecular Function: serine-type endopeptidase inhibitor activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96P63 |
| NCBI GenInfo Identifier: | 20140145 |
| NCBI Gene ID: | 89777 |
| NCBI Accession: | Q96P63.1 |
| UniProt Secondary Accession: | Q96P63,Q3SYB4 |
| UniProt Related Accession: | Q96P63 |
| Molecular Weight: | 48,446 Da |
| NCBI Full Name: | Serpin B12 |
| NCBI Synonym Full Names: | serpin family B member 12 |
| NCBI Official Symbol: | SERPINB12 |
| NCBI Official Synonym Symbols: | YUKOPIN |
| NCBI Protein Information: | serpin B12 |
| UniProt Protein Name: | Serpin B12 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB12 |
| UniProt Entry Name: | SPB12_HUMAN |
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