SDC4 Antibody (PACO52158)
- SKU:
- PACO52158
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SDC4 Antibody (PACO52158) |
| Antibody SKU: | PACO52158 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Syndecan-4 protein (19-145AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse heart tissue, Mouse kidney tissue. All lanes: SDC4 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 22, 17 kDa. Observed band size: 22 kDa. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO52158 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO52158 at dilution of 1:100. |
| Background: | Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. |
| Synonyms: | Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein), SDC4 |
| UniProt Protein Function: | syndecan-4: a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Expressed as a homodimer. Promotes cell spreading in a beta(1) integrin-dependent fashion through PKC-alpha and Rho. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 20q12 Cellular Component: lysosomal lumen; focal adhesion; costamere; cell surface; Golgi lumen; integral to plasma membrane; plasma membrane; lipid raft Molecular Function:protein binding; protein kinase C binding; fibronectin binding Biological Process: chondroitin sulfate metabolic process; glycosaminoglycan biosynthetic process; phototransduction, visible light; extracellular matrix organization and biogenesis; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; positive regulation of focal adhesion formation; ureteric bud development; positive regulation of protein kinase activity; positive regulation of stress fiber formation; carbohydrate metabolic process; pathogenesis; retinoid metabolic process |
| NCBI Summary: | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P31431 |
| NCBI GenInfo Identifier: | 38201675 |
| NCBI Gene ID: | 6385 |
| NCBI Accession: | NP_002990.2 |
| UniProt Secondary Accession: | P31431,O00773, Q16833, Q53FN9, Q6FGN3, |
| UniProt Related Accession: | P31431 |
| Molecular Weight: | 21,642 Da |
| NCBI Full Name: | syndecan-4 |
| NCBI Synonym Full Names: | syndecan 4 |
| NCBI Official Symbol: | SDC4 |
| NCBI Official Synonym Symbols: | SYND4 |
| NCBI Protein Information: | syndecan-4; amphiglycan; ryudocan amphiglycan; ryudocan core protein; syndecan proteoglycan 4; syndecan 4 (amphiglycan, ryudocan) |
| UniProt Protein Name: | Syndecan-4 |
| UniProt Synonym Protein Names: | Amphiglycan; Ryudocan core protein |
| Protein Family: | Syndecan |
| UniProt Gene Name: | SDC4 |
| UniProt Entry Name: | SDC4_HUMAN |
| Antibodies | ELISA Kits |
| Anti-SDC4 Antibody (CAB1834) | Human Syndecan 4 / SDC4 ELISA Kit |
| SDC4 Antibody (PACO03075) | Human SDC4 (Syndecan 4) CLIA Kit (HUES00943) |
| Phospho-SDC4 (S179) Antibody (PACO05002) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Rat Syndecan-4 / SDC4 ELISA Kit
Mouse Syndecan 4 / SDC4 ELISA Kit
