S100A6 Antibody (PACO20383)
- SKU:
- PACO20383
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | S100A6 Antibody (PACO20383) |
| Antibody SKU: | PACO20383 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human S100A6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20383(S100A6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20383(S100A6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. |
| Synonyms: | S100 calcium binding protein A6 |
| UniProt Protein Function: | S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; ruffle Molecular Function:calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity; tropomyosin binding Biological Process: signal transduction |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P06703 |
| NCBI GenInfo Identifier: | 116509 |
| NCBI Gene ID: | 6277 |
| NCBI Accession: | P06703.1 |
| UniProt Secondary Accession: | P06703,Q5RHS4, D3DV39, |
| UniProt Related Accession: | P06703 |
| Molecular Weight: | 10,180 Da |
| NCBI Full Name: | Protein S100-A6 |
| NCBI Synonym Full Names: | S100 calcium binding protein A6 |
| NCBI Official Symbol: | S100A6 |
| NCBI Official Synonym Symbols: | 2A9; PRA; 5B10; CABP; CACY |
| NCBI Protein Information: | protein S100-A6 |
| UniProt Protein Name: | Protein S100-A6 |
| UniProt Synonym Protein Names: | Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A6 |
| UniProt Entry Name: | S10A6_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Anti-S100A6 Antibody (CAB3461)
![Anti-S100A6 Antibody (CAB4104)[KO Validated]](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/17885/16085/anti-s100a6-antibody-cab4104ko-validated__96273__50806.1644251585.jpg?c=1 "Anti-S100A6 Antibody (CAB4104)[KO Validated]")
Porcine S100A6 ELISA Kit
