S100A6 Antibody (PACO17036)
- SKU:
- PACO17036
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | S100A6 Antibody (PACO17036) |
| Antibody SKU: | PACO17036 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human S100A6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: SKOV3 cells, A431 cells, Primary antibody: PACO17036(S100A6 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 seconds. |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. |
| Synonyms: | S100 calcium binding protein A6 |
| UniProt Protein Function: | S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; ruffle Molecular Function:calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity; tropomyosin binding Biological Process: signal transduction |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P06703 |
| NCBI GenInfo Identifier: | 116509 |
| NCBI Gene ID: | 6277 |
| NCBI Accession: | P06703.1 |
| UniProt Secondary Accession: | P06703,Q5RHS4, D3DV39, |
| UniProt Related Accession: | P06703 |
| Molecular Weight: | 10,180 Da |
| NCBI Full Name: | Protein S100-A6 |
| NCBI Synonym Full Names: | S100 calcium binding protein A6 |
| NCBI Official Symbol: | S100A6 |
| NCBI Official Synonym Symbols: | 2A9; PRA; 5B10; CABP; CACY |
| NCBI Protein Information: | protein S100-A6 |
| UniProt Protein Name: | Protein S100-A6 |
| UniProt Synonym Protein Names: | Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A6 |
| UniProt Entry Name: | S10A6_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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