Description
Antibody Name: | S100A14 Antibody (PACO45624) |
Antibody SKU: | PACO45624 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein S100-A14 protein (1-104AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO45624 at dilution of 1:100. |
Background: | Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium. |
Synonyms: | Protein S100-A14 (S100 calcium-binding protein A14) (S114), S100A14, S100A15 |
UniProt Protein Function: | S100A14: a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: cell junction; cytosol; nuclear body; perinuclear region of cytoplasm Molecular Function:chemokine receptor binding; protein binding Biological Process: defense response to bacterium; response to lipopolysaccharide; toll-like receptor 4 signaling pathway |
NCBI Summary: | This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] |
UniProt Code: | Q9HCY8 |
NCBI GenInfo Identifier: | 20178118 |
NCBI Gene ID: | 57402 |
NCBI Accession: | Q9HCY8.1 |
UniProt Secondary Accession: | Q9HCY8,Q5RHT0, |
UniProt Related Accession: | Q9HCY8 |
Molecular Weight: | 12kDa |
NCBI Full Name: | Protein S100-A14 |
NCBI Synonym Full Names: | S100 calcium binding protein A14 |
NCBI Official Symbol: | S100A14 |
NCBI Official Synonym Symbols: | BCMP84; S100A15 |
NCBI Protein Information: | protein S100-A14 |
UniProt Protein Name: | Protein S100-A14 |
UniProt Synonym Protein Names: | S100 calcium-binding protein A14; S114 |
Protein Family: | Protein |
UniProt Gene Name: | S100A14 |
Antibodies | ELISA Kits |
Anti-S100A14 Antibody (CAB10394) | Human S100A14 (S100 Calcium Binding Protein A14) ELISA Kit (HUFI06689) |
S100A14 Antibody (PACO12003) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |