S100A14 Antibody (PACO45624)
- SKU:
- PACO45624
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
| Antibody Name: | S100A14 Antibody (PACO45624) |
| Antibody SKU: | PACO45624 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein S100-A14 protein (1-104AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO45624 at dilution of 1:100. |
| Background: | Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium. |
| Synonyms: | Protein S100-A14 (S100 calcium-binding protein A14) (S114), S100A14, S100A15 |
| UniProt Protein Function: | S100A14: a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: cell junction; cytosol; nuclear body; perinuclear region of cytoplasm Molecular Function:chemokine receptor binding; protein binding Biological Process: defense response to bacterium; response to lipopolysaccharide; toll-like receptor 4 signaling pathway |
| NCBI Summary: | This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q9HCY8 |
| NCBI GenInfo Identifier: | 20178118 |
| NCBI Gene ID: | 57402 |
| NCBI Accession: | Q9HCY8.1 |
| UniProt Secondary Accession: | Q9HCY8,Q5RHT0, |
| UniProt Related Accession: | Q9HCY8 |
| Molecular Weight: | 12kDa |
| NCBI Full Name: | Protein S100-A14 |
| NCBI Synonym Full Names: | S100 calcium binding protein A14 |
| NCBI Official Symbol: | S100A14 |
| NCBI Official Synonym Symbols: | BCMP84; S100A15 |
| NCBI Protein Information: | protein S100-A14 |
| UniProt Protein Name: | Protein S100-A14 |
| UniProt Synonym Protein Names: | S100 calcium-binding protein A14; S114 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A14 |
| Antibodies | ELISA Kits |
| Anti-S100A14 Antibody (CAB10394) | Human S100A14 (S100 Calcium Binding Protein A14) ELISA Kit (HUFI06689) |
| S100A14 Antibody (PACO12003) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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