Rat JAM-A/F11R Recombinant Protein (RPES0215)
- SKU:
- RPES0215
- Product type:
- Recombinant Protein
- Host species:
- HEK293 Cells
- Reactivity:
- Rat
Frequently bought together:
Description
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Rat JAM-A/F11R Recombinant Protein
Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
| Product Name: | Rat JAM-A/F11R Recombinant Protein (RPES0215) |
| Product Code: | RPES0215 |
| Size: | 50µg |
| Species: | Rat |
| Expressed Host: | HEK293 Cells |
| Synonyms: | F11R,Jam1 |
| Accession: | Q9JHY1 |
| Sequence: | Met1-Gly238 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method |
| Protein Construction: | A DNA sequence encoding the rat F11R () was expressed, fused with the Fc region of human IgG1 at the C-terminus. |
| Purity: | > 96 % as determined by SDS-PAGE |
| Mol Mass: | 49.9 kDa |
| AP Mol Mass: | 60 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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