Rat IFN g Recombinant Protein (RPPB0402)
- SKU:
- RPPB0402
- Product type:
- Recombinant Protein
- Size:
- 100ug
- Species:
- Rat
- Target:
- IFN g
- Synonyms:
- Immune IFN
- type II IFN
- T cell IFN
- MAF
- Source:
- Escherichia Coli
- Uniprot:
- P01581
Frequently bought together:
Description
| Product Name: | Rat IFN g Recombinant Protein |
| Product Code: | RPPB0402 |
| Size: | 100µg |
| Species: | Rat |
| Target: | IFN g |
| Synonyms: | Immune IFN, type II IFN, T cell IFN, MAF, IFNG, IFG, IFI, IFN-gamma. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a 0.2?m filtered concentrated (1mg/ml) solution in PBS, pH 7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized IFN-gamma in sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized IFN-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Gly-Tyr-Leu |
| Biological Activity: | The specific activity as determined by the cytopathic affect inhibition assay with murine L929 cells chalenged with EMC virus was < 0.1 ng/ml, corresponding to a specific activity of 10,000,000units/mg. |
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I IFNs.
IFN-gamma Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 135 amino acids and having a molecular mass of 15609 Dalton.The IFN-gamma is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| NCBI Summary: | an immune molecule produced by T lymphocytes in response to mitogens or antigens [RGD, Feb 2006] |
| UniProt Code: | P01581 |
| NCBI GenInfo Identifier: | 124482 |
| NCBI Gene ID: | 25712 |
| NCBI Accession: | P01581.1 |
| UniProt Related Accession: | P01581 |
| Molecular Weight: | 17,918 Da |
| NCBI Full Name: | Interferon gamma |
| NCBI Synonym Full Names: | interferon gamma |
| NCBI Official Symbol: | Ifng |
| NCBI Official Synonym Symbols: | IFNG2 |
| NCBI Protein Information: | interferon gamma; IFN-gamma |
| UniProt Protein Name: | Interferon gamma |
| Protein Family: | Interferon |
| UniProt Gene Name: | Ifng |
| UniProt Entry Name: | IFNG_RAT |
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