PE/Cyanine5.5 Anti-Rat CD8a Antibody [OX-8] (AGEL1270)

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SKU:
AGEL1270
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Rat
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Rat CD8a Antibody [OX-8]

The Rat CD8a Monoclonal Antibody PE-Cyanine5.5 Conjugated (OX-8, AGEL1270) is a powerful tool for researchers studying CD8a, a key cell surface marker expressed on cytotoxic T cells. This monoclonal antibody, conjugated with PE-Cyanine5.5, enables the specific detection and analysis of CD8a in rat samples, making it an essential reagent for immunology and related research areas.CD8a is a crucial component of the immune system, playing a central role in the activation and function of cytotoxic T cells which are essential for immune responses against pathogens and tumors. This antibody recognizes the CD8a protein, allowing researchers to identify and analyze CD8a-expressing cells in various experimental systems.

Its specificity and high reactivity make it an invaluable tool for investigating immune responses, such as T cell activation and differentiation, in rat models.With its strong binding properties and reliable performance in various experimental techniques, the Rat CD8a Monoclonal Antibody PE-Cyanine5.5 Conjugated (OX-8, AGEL1270) is an indispensable reagent for researchers aiming to deepen their understanding of immune responses, T cell biology, and the role of CD8a in health and disease.

Product Title:PE/Cyanine5.5 Anti-Rat CD8a Antibody [OX-8]
SKU:AGEL1270
Size:25µg, 100µg
Clone No:OX-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P07725
Gene ID:24930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

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