PE Anti-Rat CD8a Antibody [OX-8] (AGEL1256)

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SKU:
AGEL1256
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Rat
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
OX-8
Conjugation:
PE
Frequently bought together:

Description

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PE Anti-Rat CD8a Antibody [OX-8]

The Rat CD8a Monoclonal Antibody PE-conjugated (OX-8) is a potent tool for researchers investigating immune responses and cell-mediated immunity in rodents. Specifically designed for detecting CD8a, a crucial cell surface marker found on cytotoxic T cells, the antibody is monoclonal in nature and conjugated with PE for efficient and sensitive detection.CD8a is a key component of the immune system, involved in the activation and regulation of cytotoxic T cells that play a pivotal role in immune surveillance and defense against pathogens. By precisely binding to the CD8a protein, this antibody enables researchers to analyze and quantify the presence of CD8a-expressing cells in various tissues and experimental models.

With applications in flow cytometry and immunofluorescence, this antibody offers an invaluable tool for studying the immune response in rat models, making it suitable for a wide range of research areas including immunology, transplantation, infectious diseases, and autoimmune disorders. Researchers can rely on the specificity and sensitivity of the OX-8 antibody to enhance their understanding of CD8a biology and its implications in immune-related processes.

Product Title:PE Anti-Rat CD8a Antibody [OX-8]
SKU:AGEL1256
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07725
Gene ID:24930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

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