FITC Anti-Rat CD8a Antibody [OX-8] (AGEL1255)

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SKU:
AGEL1255
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Rat
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Rat CD8a Antibody [OX-8]

The Rat CD8a Monoclonal Antibody (FITC Conjugated, Clone OX-8, AGEL1255) offered by Assaygenie is a powerful tool for immunology and cell biology research. Recognizing the CD8a protein, this antibody is designed for use in flow cytometry applications, enabling precise detection and analysis of CD8a expression on rat cells.CD8a is a crucial cell surface marker involved in cytotoxic T cell function and activation. By targeting CD8a, researchers can investigate immune responses, T cell development, and immune cell interactions in various experimental settings. The FITC conjugation of this antibody allows for easy visualization and quantification of CD8a-positive cells, facilitating in-depth studies on immune cell populations and functions.

With its high specificity and sensitivity, the Rat CD8a Monoclonal Antibody (FITC Conjugated, Clone OX-8, AGEL1255) provides researchers with a reliable tool for exploring the role of CD8a in immunity, infectious diseases, autoimmunity, and cancer. By understanding the expression and regulation of CD8a, new insights can be gained into immune mechanisms and potential therapeutic targets for various diseases.

Product Title:FITC Anti-Rat CD8a Antibody [OX-8]
SKU:AGEL1255
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07725
Gene ID:24930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

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