APC Anti-Rat CD8a Antibody [OX-8] (AGEL1257)

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SKU:
AGEL1257
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Rat
Applications:
FC
Frequently bought together:

Description

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APC Anti-Rat CD8a Antibody [OX-8]

The Rat CD8a Monoclonal Antibody (APC conjugated, clone OX-8, AGEL1257) is a vital tool for immunological research involving the CD8a cell surface marker in rats. This antibody, specifically designed for flow cytometry applications, has been meticulously validated for its sensitivity and specificity in detecting CD8a expression on rat cells.CD8a is a crucial marker for identifying cytotoxic T cells, a key player in the adaptive immune response. By targeting CD8a, researchers can accurately characterize T cell populations and study their functions in various experimental settings. The APC conjugated format of this antibody provides enhanced signal detection for flow cytometry, allowing for precise analysis of CD8a expression levels in rat samples.

With its high reactivity and reliability, the Rat CD8a Monoclonal Antibody (APC conjugated, clone OX-8, AGEL1257) is an essential reagent for studies focusing on T cell biology, immunology, and infectious diseases in rat models. By enabling the accurate identification and quantification of CD8a-positive cells, this antibody facilitates in-depth investigations into immune responses and the development of novel strategies for immunotherapy and disease treatment.

Product Title:APC Anti-Rat CD8a Antibody [OX-8]
SKU:AGEL1257
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07725
Gene ID:24930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

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