The Rat CD4 Domain 1 Monoclonal Antibody (AF488 conjugated, clone OX-38, AGEL1363) offered by AssayGenie is a cutting-edge tool for researchers studying the CD4 protein in rat samples. This monoclonal antibody is specifically designed for detection and analysis of CD4 Domain 1, a crucial cell surface marker involved in immune response regulation.With its AF488 conjugation, this antibody allows for fluorescent visualization of the CD4 protein, enabling precise localization and quantification in various experimental settings. The OX-38 clone provides high specificity and sensitivity, ensuring reliable results in applications such as immunofluorescence, flow cytometry, and immunohistochemistry.
CD4 Domain 1 plays a pivotal role in T cell function and immune system modulation, making it a key target for investigating immune responses, autoimmune diseases, and infectious conditions. By utilizing this monoclonal antibody, researchers can delve deeper into the mechanisms underlying CD4-mediated immune processes, paving the way for advancements in immunology research and therapeutic development.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.