The Rat CD4 Domain 1 Conjugated Monoclonal Antibody (PE/Cyanine5 Conjugated, clone OX-38, Cat. No. AGEL1359) offered by Assay Genie is a highly specific and reliable tool for research involving CD4, a crucial cell surface marker on T helper cells. This conjugated monoclonal antibody is designed to recognize the first domain of the CD4 molecule and is conjugated with PE/Cyanine5 for fluorescent detection applications.CD4 is a key glycoprotein involved in the immune system's regulation and response. By targeting the CD4 domain 1, this antibody allows for the precise detection and analysis of CD4 expression in rat samples, making it an invaluable resource for studies in immunology, inflammation, and infectious diseases.
The OX-38 clone used in this antibody is well-established and widely used in research, ensuring both high specificity and sensitivity in experimental settings.Researchers looking to investigate T cell biology, immune responses, or immunotherapy in rats can benefit from the reliable performance and versatility of the Rat CD4 Domain 1 Conjugated Monoclonal Antibody from Assay Genie. With its proven performance in flow cytometry, immunohistochemistry, and other fluorescent-based assays, this antibody is a valuable tool for advancing our understanding of immune function and developing targeted therapeutic strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.