The Rat CD4 Domain 1 Conjugated Monoclonal Antibody (PE Conjugated, clone OX-38, AGEL0388) offered by AssayGenie is a cutting-edge tool for researchers studying the CD4 protein in rats. The antibody is engineered for specific binding to CD4 Domain 1 and is conjugated with Phycoerythrin (PE) for easy detection in flow cytometry and immunofluorescence applications.CD4 is a crucial cell surface glycoprotein that plays a central role in the immune system, primarily in T cell activation and signaling. This monoclonal antibody, clone OX-38, targets Domain 1 of the CD4 molecule, enabling precise identification and visualization of CD4-expressing cells in rat samples. Its conjugation with PE further enhances the sensitivity and specificity of detection, making it an invaluable tool for immunology and cell biology research.
Researchers can utilize this antibody to explore the distribution, expression, and function of CD4 in different tissues and experimental conditions. By accurately detecting CD4-positive cells, this antibody facilitates the investigation of immune responses, T cell differentiation, and immune-mediated diseases in rat models. The Rat CD4 Domain 1 Conjugated Monoclonal Antibody (PE Conjugated, clone OX-38, AGEL0388) is a reliable reagent that empowers researchers to delve deeper into the complexities of CD4 biology and its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.