The Rat CD4 Domain 1 Conjugated Monoclonal Antibody - FITC Conjugated (OX-38) (AGEL1346) offered by AssayGenie is a cutting-edge tool for research involving the CD4 cell surface glycoprotein, a key player in the immune system. This monoclonal antibody is conjugated with FITC, allowing for easy detection and visualization of CD4 in various experimental settings.CD4, a crucial co-receptor on T cells, is involved in recognizing antigens presented by major histocompatibility complex (MHC) class II molecules. The specific binding of this antibody to the CD4 domain 1 epitope (OX-38) enables precise targeting and analysis of CD4 expression in rat samples.
This feature is particularly valuable for immunology studies focusing on T cell function, immune responses, and autoimmune diseases.By utilizing the Rat CD4 Domain 1 Conjugated Monoclonal Antibody - FITC Conjugated (OX-38) (AGEL1346), researchers can gain insights into the role of CD4 in immune regulation and inflammatory processes. This antibody is validated for use in flow cytometry, immunofluorescence, and other immunological techniques, making it a versatile tool for investigating the complex functions of CD4-positive cells in both basic and translational research studies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.