The Rat CD4 Domain 1 Conjugated Monoclonal Antibody (Biotin Conjugated, Ox-38) is a specialized research tool offered by AssayGenie, designed for the study of CD4, a key cell surface glycoprotein involved in immune function. This monoclonal antibody, specifically conjugated with biotin and targeting Domain 1 of the CD4 protein, is a valuable asset for researchers exploring immune responses and T cell biology.CD4, a crucial co-receptor for T cells, plays a pivotal role in the adaptive immune system by facilitating interactions between T cells and antigen-presenting cells. The accurate detection and analysis of CD4 expression are essential for understanding immune responses, including T cell activation, differentiation, and regulation.By utilizing the Rat CD4 Domain 1 Conjugated Monoclonal Antibody (Biotin Conjugated, Ox-38), researchers can effectively label and detect CD4 in various experimental settings, such as flow cytometry and immunohistochemistry.
This antibody enables precise identification and characterization of CD4-expressing cells, providing valuable insights into immune cell dynamics and function.With its specificity for Domain 1 of the CD4 molecule and biotin conjugation for enhanced detection capabilities, this antibody from AssayGenie is a reliable tool for investigating T cell biology, immune responses, and related research areas. Its validated performance and application versatility make it a preferred choice for immunologists, cell biologists, and cancer researchers seeking to unravel the complexities of CD4-mediated immune processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.