The Purified Human CD1a Monoclonal Antibody (OKT-6) is a cutting-edge tool for researchers delving into the intricacies of the CD1a molecule, a key component in immune system function. This monoclonal antibody, meticulously developed and purified for optimal performance, specifically targets human CD1a, offering unparalleled specificity and sensitivity in various experimental setups.With origins in innovative biotechnology, the OKT-6 Antibody is a reliable partner in studies exploring immunology, infectious diseases, and dermatology. By precisely binding to the CD1a protein, this antibody enables precise detection and characterization of CD1a in diverse cell types and biological samples. Its versatility extends to applications such as flow cytometry, immunohistochemistry, and immunoprecipitation, opening avenues for detailed investigations into immune responses and pathogenic mechanisms.
CD1a, a crucial player in antigen presentation and immune surveillance, holds pivotal roles in immune-mediated diseases, allergies, and host-pathogen interactions. Research involving CD1a monoclonal antibodies like OKT-6 offers insights into immune cell activation, T cell responses, and the development of novel therapies for conditions where the immune system is either the hero or the villain.Elevate your research capabilities with the Purified Human CD1a Monoclonal Antibody (OKT-6) - an indispensable resource for unraveling the complexities of immune regulation and immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.