PTX3 Antibody (PACO20721)
- SKU:
- PACO20721
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PTX3 Antibody (PACO20721) |
| Antibody SKU: | PACO20721 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human PTX3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20721(PTX3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Hepg2 cells, Primary antibody: PACO20721(PTX3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20721(PTX3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. |
| Synonyms: | pentraxin 3, long |
| UniProt Protein Function: | PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 3q25 Cellular Component: extracellular space; extracellular region Molecular Function:complement component C1q binding; zymosan binding; virion binding Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response |
| UniProt Code: | P26022 |
| NCBI GenInfo Identifier: | 296452984 |
| NCBI Gene ID: | 5806 |
| NCBI Accession: | P26022.3 |
| UniProt Secondary Accession: | P26022,Q38M82, B2R6T6, |
| UniProt Related Accession: | P26022 |
| Molecular Weight: | 41,976 Da |
| NCBI Full Name: | Pentraxin-related protein PTX3 |
| NCBI Synonym Full Names: | pentraxin 3, long |
| NCBI Official Symbol: | PTX3 |
| NCBI Official Synonym Symbols: | TSG-14; TNFAIP5 |
| NCBI Protein Information: | pentraxin-related protein PTX3; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5 |
| UniProt Protein Name: | Pentraxin-related protein PTX3 |
| UniProt Synonym Protein Names: | Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14 |
| Protein Family: | Pentraxin-related protein |
| UniProt Gene Name: | PTX3 |
| UniProt Entry Name: | PTX3_HUMAN |
| Antibodies | ELISA Kits |
| Anti-PTX3 Antibody (CAB12669) | Human Pentraxin-related protein PTX3 (PTX3) ELISA Kit |
| Anti-PTX3 Antibody (CAB12670) | |
| PTX3 Antibody (PACO01378) | |
| PTX3 Antibody (PACO11608) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Anti-PTX3 Antibody (CAB12670)
Anti-PTX3 Antibody (CAB12669)
Human Pentraxin-related protein PTX3 (PTX3) ELISA Kit
