PRPF40A Antibody (PACO61582)
- SKU:
- PACO61582
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PRPF40A Antibody (PACO61582) |
| Antibody SKU: | PACO61582 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pre-mRNA-processing factor 40 homolog A protein (120-266AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: U251 whole cell lysate, Hela whole cell lysate, 293T whole cell lysate. All lanes: PRPF40A antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 109, 106, 107, 11 kDa. Observed band size: 109 kDa. |
 | IHC image of PACO61582 diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. |
| Synonyms: | Pre-mRNA-processing factor 40 homolog A, Fas ligand-associated factor 1, Formin-binding protein 11, Formin-binding protein 3, Huntingtin yeast partner A, Huntingtin-interacting protein 10, HIP-10, Huntingtin-interacting protein A, Renal carcinoma antigen NY-REN-6, PRPF40A, FBP11, FLAF1, FNBP3, HIP10, HYPA, HSPC225 |
| UniProt Protein Function: | FNBP3: Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. Belongs to the PRPF40 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; SpliceosomeChromosomal Location of Human Ortholog: 2q23.3Cellular Component: cytoplasm; membrane; nuclear matrix; nucleoplasm; snRNP U1Molecular Function: protein binding; RNA bindingBiological Process: cell migration; cytoskeleton organization and biogenesis; nuclear mRNA splicing, via spliceosome; regulation of cell shape; regulation of cytokinesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O75400 |
| NCBI GenInfo Identifier: | 3341990 |
| NCBI Gene ID: | 55660 |
| NCBI Accession: | AAC27506.1 |
| UniProt Secondary Accession: | O75400,O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2 Q9Y5A8 |
| UniProt Related Accession: | O75400 |
| Molecular Weight: | 10,697 Da |
| NCBI Full Name: | huntingtin-interacting protein HYPA/FBP11, partial |
| NCBI Synonym Full Names: | pre-mRNA processing factor 40 homolog A |
| NCBI Official Symbol: | PRPF40A |
| NCBI Official Synonym Symbols: | HYPA; FBP11; FLAF1; FNBP3; HIP10; Prp40; FBP-11; HIP-10; NY-REN-6 |
| NCBI Protein Information: | pre-mRNA-processing factor 40 homolog A |
| UniProt Protein Name: | Pre-mRNA-processing factor 40 homolog A |
| UniProt Synonym Protein Names: | Fas ligand-associated factor 1; Formin-binding protein 11; Formin-binding protein 3; Huntingtin yeast partner A; Huntingtin-interacting protein 10; HIP-10; Huntingtin-interacting protein A; Renal carcinoma antigen NY-REN-6 |
| Protein Family: | Hydrophobin |
| UniProt Gene Name: | PRPF40A |
| UniProt Entry Name: |
| Antibodies |
| PRPF40A Antibody (PACO11498) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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