Prl Antibody (PACO60793)
- SKU:
- PACO60793
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Prl Antibody (PACO60793) |
| Antibody SKU: | PACO60793 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Prolactin protein (30-226AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO60793 diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Prolactin acts primarily on the mammary gland by promoting lactation. |
| Synonyms: | Prolactin (PRL), Prl |
| UniProt Protein Function: | prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. |
| UniProt Protein Details: | Protein type:Secreted; Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide Cellular Component: extracellular region; secretory granule Molecular Function:prolactin receptor binding; hormone activity Biological Process: response to drug; circadian rhythm; lactation; maternal behavior; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; response to organic cyclic substance; response to estradiol stimulus; cellular response to hormone stimulus; response to ethanol; regulation of JAK-STAT cascade; ovulation cycle; mammary gland development; positive regulation of cell proliferation; parturition; regulation of ossification; multicellular organismal response to stress; positive regulation of epithelial cell proliferation; response to nutrient; STAT protein nuclear translocation |
| NCBI Summary: | induces lactation; may facilitate decidual growth and placentation; promotes prostate epithelial cell proliferation [RGD, Feb 2006] |
| UniProt Code: | P01237 |
| NCBI GenInfo Identifier: | 130938 |
| NCBI Gene ID: | 24683 |
| NCBI Accession: | P01237.1 |
| UniProt Secondary Accession: | P01237,P70520, |
| UniProt Related Accession: | P01237 |
| Molecular Weight: | 25,753 Da |
| NCBI Full Name: | Prolactin |
| NCBI Synonym Full Names: | prolactin |
| NCBI Official Symbol: | Prl |
| NCBI Official Synonym Symbols: | PRLB; Prol; PRLSD1; Prl1a1; RNPROL; RATPRLSD1 |
| NCBI Protein Information: | prolactin; prolactin family 1, subfamily a, member 1 |
| UniProt Protein Name: | Prolactin |
| Protein Family: | Prolactin |
| UniProt Gene Name: | Prl |
| UniProt Entry Name: | PRL_RAT |
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