Pleiotrophin/PTN/HB-GAM Recombinant Protein (RPES0888)

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SKU:
RPES0888
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
Frequently bought together:

Description

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Pleiotrophin/PTN/HB-GAM Recombinant Protein

Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50% amino acid (aa) sequence identity, share some functions, and constitute a family. PTN is a highly conserved protein? human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity orgreater. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated withneuronal development or stresses such as brain ischemia and Parkinson’s disease.

Product Name:Pleiotrophin/PTN/HB-GAM Recombinant Protein (RPES0888)
Product Code:RPES0888
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Osteoblast-specific factor 1, OSF-1,HARP,HB-GAM,HBBN,HBNF,OSF,Osf-1,Osf1
Accession:P63089
Sequence:Gly33-Asp168
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Pleiotrophin is produced by our Mammalian expression system and the target gene encoding Gly33-Asp168 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:16.1 kDa
AP Mol Mass:18 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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