Anti-Plaur 항체의 (PACO28986)

Antibody Name:	Plaur Antibody (PACO28986)
Antibody SKU:	PACO28986
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:	Rat, Human
Immunogen:	Recombinant Rat Urokinase plasminogen activator surface receptor ptotein (25-299AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot
All lanes: Plaur antibody at 2µg/ml
Lane 1: 293T whole cell lysate
Lane 2: Rat brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 36, 25 kDa
Observed band size: 36 kDa
.

Background:	Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
Synonyms:	Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (CD_antigen: CD87), Plaur

UniProt Protein Function:	uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cell surface; extracellular region; focal adhesion; integral component of plasma membrane; plasma membrane Molecular Function:enzyme binding; protein domain specific binding; receptor binding; U-plasminogen activator receptor activity Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein phosphorylation; regulation of proteolysis; skeletal muscle tissue regeneration; spermatogenesis
NCBI Summary:	receptor for urokinase-plasminogen activator; may play a central role in malignant tumour progression [RGD, Feb 2006]
UniProt Code:	P49616
NCBI GenInfo Identifier:	8394516
NCBI Gene ID:	50692
NCBI Accession:	NP_059046.1
UniProt Secondary Accession:	P49616,O35771, P51573, Q7TN35,
UniProt Related Accession:	P49616
Molecular Weight:	24,417 Da
NCBI Full Name:	urokinase plasminogen activator surface receptor isoform 2
NCBI Synonym Full Names:	plasminogen activator, urokinase receptor
NCBI Official Symbol:	Plaur
NCBI Official Synonym Symbols:	Par; uPAR; Plaur3; uPAR-2; uPAR-3
NCBI Protein Information:	urokinase plasminogen activator surface receptor
UniProt Protein Name:	Urokinase plasminogen activator surface receptor
UniProt Synonym Protein Names:	CD_antigen: CD87
UniProt Gene Name:	Plaur

ELISA Kits

Rat uPAR ELISA Kit

Rat PLAUR/uPAR (Plasminogen Activator, Urokinase Receptor) CLIA Kit (RTES00586)

Rat Urokinase plasminogen activator surface receptor (Plaur) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)