Phospho-PLD1 (S561) Antibody (PACO04607)
- SKU:
- PACO04607
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Phospho-PLD1 (S561) Antibody |
| Antibody SKU: | PACO04607 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from human PC-PLD1 around the phosphorylation site of S561. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | PLD1; Phospholipase D1; PLD 1; hPLD1; Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1 |
| UniProt Protein Function: | PLD1: a phosphatidylcholine-hydrolyzing phospholipase. Activated by ADP-ribosylated Rho and protein kinase C. Implicated as a critical step in numerous cellular pathways including membrane trafficking and the regulation polymorphonuclear leukocyte degranulation and oxidant production. May be involved in the regulation of perinuclear intravesicular membrane traffic. Four splice-variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Phospholipase; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; EC 3.1.4.4; Lipid Metabolism - ether lipid Chromosomal Location of Human Ortholog: 3q26 Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; perinuclear region of cytoplasm; late endosome membrane; lysosomal membrane; endocytic vesicle; apical plasma membrane; endosome Molecular Function:protein binding; phospholipase D activity; phosphoinositide binding Biological Process: defense response to Gram-positive bacterium; phosphatidylglycerol biosynthetic process; small GTPase mediated signal transduction; phospholipid metabolic process; glycerophospholipid biosynthetic process; Ras protein signal transduction; phosphatidic acid biosynthetic process; chemotaxis; lipid catabolic process; regulation of microvillus biogenesis |
| NCBI Summary: | This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q13393 |
| NCBI GenInfo Identifier: | 4505873 |
| NCBI Gene ID: | 5337 |
| NCBI Accession: | NP_002653.1 |
| UniProt Related Accession: | Q13393 |
| Molecular Weight: | |
| NCBI Full Name: | phospholipase D1 isoform a |
| NCBI Synonym Full Names: | phospholipase D1 |
| NCBI Official Symbol: | PLD1 |
| NCBI Official Synonym Symbols: | CVDD |
| NCBI Protein Information: | phospholipase D1 |
| UniProt Protein Name: | Phospholipase D1 |
| UniProt Synonym Protein Names: | Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1 |
| Protein Family: | Phospholipase |
| UniProt Gene Name: | PLD1 |
| UniProt Entry Name: | PLD1_HUMAN |
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Human PLD1 ELISA Kit
