Phospho-NUDC (Ser326) Antibody (PACO24533)
- SKU:
- PACO24533
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Phospho-NUDC (Ser326) Antibody (PACO24533) |
| Antibody SKU: | PACO24533 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:1000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Peptide sequence around phosphorylation site of serine 326 (D-F-S(p)-K-A) derived from Human NudC. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from rat brain cells, using NudC (Phospho-Ser326) antibody. The lane on the right is treated with the synthesized peptide. |
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NudC (Phospho-Ser326) antibody. The picture on the right is treated with the synthesized peptide. |
 | Western blot analysis of extracts from HepG2 cells (Lane 2), using NudC (Phospho-Ser326) Antibody. The lane on the left is treated with synthesized peptide. |
| Background: | Plays a role in neurogenesis and neuronal migration By similarity. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation. |
| Synonyms: | MNUDC protein; Nuclear distribution gene C (A.nidulans) homolog; SIG-92 |
| UniProt Protein Function: | NUDC: a cytoskeletal protein that is a component of the dynactin complex. The cytoplasmic dynein/dynactin complex, a minus-end-directed motor, powers various) aspects of mitosis, including establishment of bipolarity, organization of spindle poles, alignment and segregation of chromosomes, as well as regulation of microtubule dynamics. Phosphorylation by PLK1 may play a critical role in cytokinesis. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Cytoskeletal Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: cytoplasm; cytosol; nucleoplasm Molecular Function:protein binding Biological Process: cell proliferation; multicellular organismal development; sister chromatid cohesion |
| NCBI Summary: | This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9Y266 |
| NCBI GenInfo Identifier: | 62287138 |
| NCBI Gene ID: | 10726 |
| NCBI Accession: | Q9Y266.1 |
| UniProt Secondary Accession: | Q9Y266,Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6, |
| UniProt Related Accession: | Q9Y266 |
| Molecular Weight: | 38,243 Da |
| NCBI Full Name: | Nuclear migration protein nudC |
| NCBI Synonym Full Names: | nuclear distribution C, dynein complex regulator |
| NCBI Official Symbol: | NUDC |
| NCBI Official Synonym Symbols: | HNUDC; MNUDC; NPD011 |
| NCBI Protein Information: | nuclear migration protein nudC |
| UniProt Protein Name: | Nuclear migration protein nudC |
| UniProt Synonym Protein Names: | Nuclear distribution protein C homolog |
| Protein Family: | NADH pyrophosphatase |
| UniProt Gene Name: | NUDC |
| UniProt Entry Name: | NUDC_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human NUDC ELISA Kit (HUFI07456)
