PFKFB2 Antibody (PACO11183)

(No reviews yet) Write a Review
SKU:
PACO11183
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Application:
WB
Antibody type:
Polyclonal
Conjugation:
Unconjugated
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:PFKFB2 Antibody (PACO11183)
Antibody SKU:PACO11183
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human PFKFB2
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2;PFKFB2;DKFZp781D2217;MGC138308;MGC138310;PFK-2/FBPase-2 ;
UniProt Protein Function:PFKFB2: a bifunctional heterodimeric enzyme involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. Regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. Two splice-variant isoforms have been described.
UniProt Protein Details:

Protein type:EC 3.1.3.46; Carbohydrate Metabolism - fructose and mannose; EC 2.7.1.105; Kinase, other; Phosphatase (non-protein); Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q31

Cellular Component: cytosol

Molecular Function:6-phosphofructo-2-kinase activity; protein binding; protein kinase binding

Biological Process: glycolysis

NCBI Summary:The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O60825
NCBI GenInfo Identifier:12643333
NCBI Gene ID:5208
NCBI Accession:O60825.2
UniProt Secondary Accession:O60825,O60824, Q5VVQ3, Q5VVQ4, Q9H3P1,
UniProt Related Accession:O60825
Molecular Weight:54,406 Da
NCBI Full Name:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
NCBI Synonym Full Names:6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
NCBI Official Symbol:PFKFB2  
NCBI Official Synonym Symbols:PFK-2/FBPase-2  
NCBI Protein Information:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
UniProt Protein Name:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
UniProt Synonym Protein Names:6PF-2-K/Fru-2,6-P2ase heart-type isozymeIncluding the following 2 domains:6-phosphofructo-2-kinase (EC:2.7.1.105)Fructose-2,6-bisphosphatase (EC:3.1.3.46)
Protein Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
UniProt Gene Name:PFKFB2  
UniProt Entry Name:F262_HUMAN

0 Reviews

View AllClose

Related Products