PEG10 Antibody (PACO11164)

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SKU:
PACO11164
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Application:
WB
Application:
IHC
Application:
IF
Antibody type:
Polyclonal
Conjugation:
Unconjugated
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:PEG10 Antibody (PACO11164)
Antibody SKU:PACO11164
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Human PEG10
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:paternally expressed 10;PEG10;Edr;HB-1;KIAA1051;MEF3L;Mar2;Mart2;RGAG3 ;
UniProt Protein Function:PEG10: Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation. May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter. Up-regulated by MYC and dihydrotestosteron (DHT). Interacts with ALK1, SIAH1 and SIAH2. 2 isoforms of the human protein are produced by ribosomal frameshifting.
UniProt Protein Details:

Protein type:RNA-binding; Cell cycle regulation; Apoptosis; Cell development/differentiation

Chromosomal Location of Human Ortholog: 7q21

Cellular Component: cytoplasm; nucleus

Molecular Function:protein binding; DNA binding; zinc ion binding

Biological Process: apoptosis; cell differentiation; negative regulation of transforming growth factor beta receptor signaling pathway

UniProt Code:Q86TG7
NCBI GenInfo Identifier:172046699
NCBI Gene ID:
NCBI Accession:Q86TG7.2
Molecular Weight:55kDa
NCBI Full Name:Retrotransposon-derived protein PEG10
UniProt Protein Name:Retrotransposon-derived protein PEG10
UniProt Synonym Protein Names:Embryonal carcinoma differentiation-regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3-like protein 1; MEF3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Ty3/Gypsy-like protein
Protein Family:Retrotransposon-derived protein
UniProt Gene Name:PEG10  
UniProt Entry Name:PEG10_HUMAN

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