PCDH11X Antibody (PACO58484)
- SKU:
- PACO58484
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | PCDH11X Antibody (PACO58484) |
| Antibody SKU: | PACO58484 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:500-1:1000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protocadherin-11 X-linked protein (987-1117AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58484 diluted at 1:500 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of HepG2 cells with PACO58484 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Potential calcium-dependent cell-adhesion protein. |
| Synonyms: | Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S), PCDH11X, KIAA1326 PCDH11 PCDHX |
| UniProt Protein Function: | PCDH11X: Potential calcium-dependent cell-adhesion protein. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq21.3Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q9BZA7 |
| NCBI GenInfo Identifier: | 74761344 |
| NCBI Gene ID: | 27328 |
| NCBI Accession: | Q9BZA7.1 |
| UniProt Secondary Accession: | Q9BZA7,Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7 Q70LS8, Q70LS9, Q70LT7 |
| UniProt Related Accession: | Q9BZA7 |
| Molecular Weight: | 1347 |
| NCBI Full Name: | Protocadherin-11 X-linked |
| NCBI Synonym Full Names: | protocadherin 11 X-linked |
| NCBI Official Symbol: | PCDH11X |
| NCBI Official Synonym Symbols: | PCDHX; PCDH-X; PCDH11; PPP1R119 |
| NCBI Protein Information: | protocadherin-11 X-linked; protocadherin-S; protocadherin 11X; protocadherin on the X chromosome; protein phosphatase 1, regulatory subunit 119 |
| UniProt Protein Name: | Protocadherin-11 X-linked |
| UniProt Synonym Protein Names: | Protocadherin on the X chromosome; PCDH-X; Protocadherin-S |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH11X |
| UniProt Entry Name: | PC11X_HUMAN |
| Antibodies |
| PCDH11X Antibody (PACO11093) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
