| UniProt Protein Function: | PCDH11X: Potential calcium-dependent cell-adhesion protein. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq21.3Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Code: | Q9BZA7 |
| NCBI GenInfo Identifier: | 74761344 |
| NCBI Gene ID: | 27328 |
| NCBI Accession: | Q9BZA7.1 |
| UniProt Secondary Accession: | Q9BZA7,Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7 Q70LS8, Q70LS9, Q70LT7 |
| UniProt Related Accession: | Q9BZA7 |
| Molecular Weight: | 1347 |
| NCBI Full Name: | Protocadherin-11 X-linked |
| NCBI Synonym Full Names: | protocadherin 11 X-linked |
| NCBI Official Symbol: | PCDH11X |
| NCBI Official Synonym Symbols: | PCDHX; PCDH-X; PCDH11; PPP1R119 |
| NCBI Protein Information: | protocadherin-11 X-linked; protocadherin-S; protocadherin 11X; protocadherin on the X chromosome; protein phosphatase 1, regulatory subunit 119 |
| UniProt Protein Name: | Protocadherin-11 X-linked |
| UniProt Synonym Protein Names: | Protocadherin on the X chromosome; PCDH-X; Protocadherin-S |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH11X |
| UniProt Entry Name: | PC11X_HUMAN |
