ORF3 Antibody (PACO35150)
- SKU:
- PACO35150
- Product type:
- Antibody
- Reactivity:
- Hepatitis E virus genotype 1
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ORF3 Antibody (PACO35150) |
Antibody SKU: | PACO35150 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Hepatitis E virus genotype 1 |
Immunogen: | Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways. |
Synonyms: | Protein ORF3 (pORF3), ORF3 |
UniProt Protein Function: | May act as a viral regulatory protein involved in the modulation of mitogenic signaling pathways. May be involved in virion morphogenesis and viral pathogenesis. Expedites the processing and secretion of AMBP from the hepatocyte. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O90299 |
NCBI GenInfo Identifier: | 189036527 |
NCBI Gene ID: | |
NCBI Accession: | O90299.2 |
UniProt Secondary Accession: | O90299,Q68984 |
UniProt Related Accession: | O90299 |
Molecular Weight: | 27.8kD |
NCBI Full Name: | Protein ORF3 |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | Protein ORF3 |
UniProt Synonym Protein Names: | |
Protein Family: | Protein |
UniProt Gene Name: | ORF3 |
UniProt Entry Name: |