| UniProt Protein Function: | NUDC: a cytoskeletal protein that is a component of the dynactin complex. The cytoplasmic dynein/dynactin complex, a minus-end-directed motor, powers various) aspects of mitosis, including establishment of bipolarity, organization of spindle poles, alignment and segregation of chromosomes, as well as regulation of microtubule dynamics. Phosphorylation by PLK1 may play a critical role in cytokinesis. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Cytoskeletal Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: cytoplasm; cytosol; nucleoplasm Molecular Function:protein binding Biological Process: cell proliferation; multicellular organismal development; sister chromatid cohesion |
| NCBI Summary: | This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9Y266 |
| NCBI GenInfo Identifier: | 62287138 |
| NCBI Gene ID: | 10726 |
| NCBI Accession: | Q9Y266.1 |
| UniProt Secondary Accession: | Q9Y266,Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6, |
| UniProt Related Accession: | Q9Y266 |
| Molecular Weight: | 38,243 Da |
| NCBI Full Name: | Nuclear migration protein nudC |
| NCBI Synonym Full Names: | nuclear distribution C, dynein complex regulator |
| NCBI Official Symbol: | NUDC |
| NCBI Official Synonym Symbols: | HNUDC; MNUDC; NPD011 |
| NCBI Protein Information: | nuclear migration protein nudC |
| UniProt Protein Name: | Nuclear migration protein nudC |
| UniProt Synonym Protein Names: | Nuclear distribution protein C homolog |
| Protein Family: | NADH pyrophosphatase |
| UniProt Gene Name: | NUDC |
| UniProt Entry Name: | NUDC_HUMAN |
