NOTUM Antibody (PACO48658)
- SKU:
- PACO48658
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | NOTUM Antibody (PACO48658) |
| Antibody SKU: | PACO48658 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue, Mouse stomach tissue. All lanes: NOTUM antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 56 kDa. Observed band size: 56 kDa.. |
| Background: | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleylation of WNT proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors. |
| Synonyms: | Palmitoleoyl-protein carboxylesterase NOTUM (EC 3.1.1.98) (hNOTUM), NOTUM |
| UniProt Protein Function: | NOTUM: May deacetylate GlcNAc residues on cell surface glycans (Potential). Belongs to the pectinacetylesterase family. |
| UniProt Protein Details: | Protein type:EC 3.-.-.-; Secreted; Hydrolase; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: extracellular region Molecular Function:phospholipase C activity Biological Process: negative regulation of Wnt receptor signaling pathway |
| UniProt Code: | Q6P988 |
| NCBI GenInfo Identifier: | 182628300 |
| NCBI Gene ID: | 147111 |
| NCBI Accession: | Q6P988.2 |
| UniProt Secondary Accession: | Q6P988,Q8N410, Q8NI82, |
| UniProt Related Accession: | Q6P988 |
| Molecular Weight: | 55,699 Da |
| NCBI Full Name: | Palmitoleoyl-protein carboxylesterase NOTUM |
| NCBI Synonym Full Names: | NOTUM, palmitoleoyl-protein carboxylesterase |
| NCBI Official Symbol: | NOTUM |
| NCBI Official Synonym Symbols: | hNOTUM |
| NCBI Protein Information: | palmitoleoyl-protein carboxylesterase NOTUM |
| UniProt Protein Name: | Palmitoleoyl-protein carboxylesterase NOTUM |
| UniProt Synonym Protein Names: | hNOTUM |
| Protein Family: | Palmitoleoyl-protein carboxylesterase |
| UniProt Gene Name: | NOTUM |
| UniProt Entry Name: | NOTUM_HUMAN |
| Antibodies | ELISA Kits |
| Anti-NOTUM Antibody (CAB16600) | Human NOTUM / Protein notum homolog ELISA Kit |
| Human Protein notum homolog (NOTUM) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Anti-NOTUM Antibody (CAB16600)
Human Protein notum homolog (NOTUM) ELISA Kit
Human NOTUM / Protein notum homolog ELISA Kit
Human TP53 antibody(p53 antibody) ELISA Kit
