NDUFAF1 Antibody (PACO16744)
- SKU:
- PACO16744
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | NDUFAF1 Antibody (PACO16744) |
| Antibody SKU: | PACO16744 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human NDUFAF1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 cells, Jurkat cells, Primary antibody: PACO16744(NDUFAF1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
| Background: | This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. |
| Synonyms: | NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 |
| UniProt Protein Function: | NDUFAF1: Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Belongs to the CIA30 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 15q11.2-q21.3 Cellular Component: cytoplasm; mitochondrial inner membrane Molecular Function:protein binding Biological Process: mitochondrial respiratory chain complex I assembly Disease: Mitochondrial Complex I Deficiency |
| NCBI Summary: | This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q9Y375 |
| NCBI GenInfo Identifier: | 21542405 |
| NCBI Gene ID: | 51103 |
| NCBI Accession: | Q9Y375.2 |
| UniProt Secondary Accession: | Q9Y375,Q9BVZ5, |
| UniProt Related Accession: | Q9Y375 |
| Molecular Weight: | 37,764 Da |
| NCBI Full Name: | Complex I intermediate-associated protein 30, mitochondrial |
| NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase complex assembly factor 1 |
| NCBI Official Symbol: | NDUFAF1 |
| NCBI Official Synonym Symbols: | CGI65; CIA30; CGI-65 |
| NCBI Protein Information: | complex I intermediate-associated protein 30, mitochondrial |
| UniProt Protein Name: | Complex I intermediate-associated protein 30, mitochondrial |
| UniProt Synonym Protein Names: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1 |
| UniProt Gene Name: | NDUFAF1 |
| UniProt Entry Name: | CIA30_HUMAN |
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