MUC6 Antibody (PACO18712)
- SKU:
- PACO18712
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MUC6 Antibody (PACO18712) |
Antibody SKU: | PACO18712 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human MUC6 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO18712(MUC6 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18712(MUC6 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid, secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
Synonyms: | mucin 6, oligomeric mucus/gel-forming |
UniProt Protein Function: | MUC6: May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: Golgi lumen; extracellular region Molecular Function:extracellular matrix structural constituent Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; maintenance of gastrointestinal epithelium; post-translational protein modification |
NCBI Summary: | The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010] |
UniProt Code: | Q6W4X9 |
NCBI GenInfo Identifier: | 151301154 |
NCBI Gene ID: | 4588 |
NCBI Accession: | NP_005952.2 |
UniProt Secondary Accession: | Q6W4X9,O15329, Q14394, Q2TUQ5, Q4L207, Q8N8I1, Q8NAK1 |
UniProt Related Accession: | Q6W4X9 |
Molecular Weight: | 257,051 Da |
NCBI Full Name: | mucin-6 |
NCBI Synonym Full Names: | mucin 6, oligomeric mucus/gel-forming |
NCBI Official Symbol: | MUC6 |
NCBI Official Synonym Symbols: | MUC-6 |
NCBI Protein Information: | mucin-6; gastric mucin-6 |
UniProt Protein Name: | Mucin-6 |
UniProt Synonym Protein Names: | Gastric mucin-6 |
Protein Family: | Mucin |
UniProt Gene Name: | MUC6 |
UniProt Entry Name: | MUC6_HUMAN |
ELISA Kits |
Human Mucin 6 / MUC6 ELISA Kit |
Human MUC6 (Mucin 6) CLIA Kit (HUES00454) |
Human MUC6 (Mucin 6) ELISA Kit (HUES01867) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |