| UniProt Protein Function: | MRPS10: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008]Protein type: MitochondrialChromosomal Location of Human Ortholog: 6p21.1Cellular Component: mitochondrial inner membrane; mitochondrionBiological Process: positive regulation of defense response to virus by host |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S10P family. Pseudogenes corresponding to this gene are found on chromosomes 1q, 3p, and 9p. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P82664 |
| NCBI GenInfo Identifier: | 20140017 |
| NCBI Gene ID: | 55173 |
| NCBI Accession: | P82664.2 |
| UniProt Secondary Accession: | P82664,Q9H3E5, Q9NVR3, B2RE89 |
| UniProt Related Accession: | P82664 |
| Molecular Weight: | 22,999 Da |
| NCBI Full Name: | 28S ribosomal protein S10, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S10 |
| NCBI Official Symbol: | MRPS10 |
| NCBI Official Synonym Symbols: | MRP-S10; PNAS-122 |
| NCBI Protein Information: | 28S ribosomal protein S10, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S10, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS10 |
| UniProt Entry Name: | RT10_HUMAN |
