MRPL21 Antibody (PACO01096)
- SKU:
- PACO01096
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MRPL21 Antibody |
Antibody SKU: | PACO01096 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human MRP-L21. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21 |
UniProt Protein Function: | MRPL21: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]Protein type: Ribosomal; MitochondrialChromosomal Location of Human Ortholog: 11q13.3Cellular Component: mitochondrial inner membrane; ribosomeMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008] |
UniProt Code: | Q7Z2W9 |
NCBI GenInfo Identifier: | 31652228 |
NCBI Gene ID: | 219927 |
NCBI Accession: | NP_852616.1 |
UniProt Secondary Accession: | Q7Z2W9,A6NKU0, C9JPR2 |
UniProt Related Accession: | Q7Z2W9 |
Molecular Weight: | 13,746 Da |
NCBI Full Name: | 39S ribosomal protein L21, mitochondrial isoform a |
NCBI Synonym Full Names: | mitochondrial ribosomal protein L21 |
NCBI Official Symbol: | MRPL21 |
NCBI Official Synonym Symbols: | L21mt; MRP-L21 |
NCBI Protein Information: | 39S ribosomal protein L21, mitochondrial |
UniProt Protein Name: | 39S ribosomal protein L21, mitochondrial |
UniProt Synonym Protein Names: | |
Protein Family: | 39S ribosomal protein |
UniProt Gene Name: | MRPL21 |
UniProt Entry Name: | RM21_HUMAN |