The Mouse TCR Monoclonal Antibody (PE/Cyanine7 Conjugated, H57-597/HB218) is a powerful tool for researchers studying the T-cell receptor (TCR) in mouse samples. This antibody, conjugated to PE/Cyanine7 for fluorescent detection, specifically targets the TCR complex, allowing for precise identification and analysis of T cells in various experimental setups.The TCR plays a vital role in the adaptive immune response by recognizing specific antigens presented by major histocompatibility complex (MHC) molecules. The H57-597/HB218 antibody is well-suited for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, enabling researchers to delve deeper into the diversity and functionality of T cells in the context of immunology, infectious diseases, and autoimmune conditions.
By utilizing this monoclonal antibody, researchers can elucidate the intricacies of T-cell-mediated immune responses, investigate TCR signaling pathways, and explore the dynamics of T-cell populations in various biological systems. Its high specificity, sensitivity, and reproducibility make it an indispensable tool for advancing our understanding of T-cell biology and its implications in health and disease.
PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.