The Mouse TCR Monoclonal Antibody (AF647-conjugated) H57-597 (HB218) (AGEL1555) is a highly specific and versatile tool for researchers focusing on immune responses and T cell receptor (TCR) signaling pathways. This monoclonal antibody is designed to target the TCR molecule in mouse samples and is conjugated with AF647 for easy detection in various experimental settings.The TCR plays a crucial role in the recognition of antigens by T cells, leading to immune responses against pathogens, infected cells, and cancerous cells. The H57-597 (HB218) monoclonal antibody specifically binds to the TCR, allowing researchers to study T cell activation, differentiation, and effector functions in depth.
Utilizing this antibody in immunology research can provide valuable insights into the mechanisms of T cell-mediated immune responses, tolerance, and autoimmune diseases. By understanding the intricate details of TCR signaling, researchers can develop novel therapeutic strategies for immune-related disorders and diseases.Overall, the Mouse TCR Monoclonal Antibody (AF647-conjugated) H57-597 (HB218) (AGEL1555) is a reliable tool that facilitates the investigation of TCR functionality and T cell biology, making it an essential component of studies focused on immunology, infectious diseases, and cancer immunotherapy.
Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.