The Mouse TCR Monoclonal Antibody (AF647 conjugated) - H57-597/HB218 (AGEL1546) from AssayGenie is a cutting-edge tool designed for research involving T cell receptors (TCR) in mice. This monoclonal antibody is conjugated with AF647, a fluorescent dye that enables highly sensitive detection in immunofluorescence applications. It specifically targets the H57-597 and HB218 epitopes of the TCR, allowing for precise identification and analysis of TCR-expressing cells.The TCR is a crucial component of the adaptive immune system, responsible for recognizing antigens presented by major histocompatibility complex (MHC) molecules. By targeting specific TCR epitopes, researchers can gain insights into T cell activation, differentiation, and function in various immunological contexts.
This antibody is validated for use in flow cytometry, immunofluorescence microscopy, and other techniques, making it a versatile tool for studying T cell biology.With its high specificity and sensitivity, the Mouse TCR Monoclonal Antibody (AF647 conjugated) - H57-597/HB218 (AGEL1546) is an essential reagent for immunology research, vaccine development, and studies on T cell-mediated immune responses. Its ability to selectively bind to TCR epitopes in mouse models opens up new possibilities for investigating immune-related mechanisms and developing targeted therapies for infectious diseases, autoimmune disorders, and cancer. Advance your research with this powerful antibody from AssayGenie.
Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.