The Mouse TCR Monoclonal Antibody (AF488-conjugated, H57-597/HB218) is a cutting-edge research tool designed for investigating T cell receptor (TCR) expression in mouse samples. This antibody, conjugated with AF488 for fluorescent detection, specifically targets the TCR molecules H57-597 and HB218, allowing for precise visualization and analysis in flow cytometry and immunofluorescence assays.TCR plays a pivotal role in the adaptive immune response by recognizing antigens presented by major histocompatibility complex (MHC) molecules. The utilization of this monoclonal antibody provides researchers with a valuable tool for studying T cell activation, differentiation, and function in various experimental models.
The high specificity and sensitivity of the antibody ensure reliable and reproducible results in immunology research, particularly in studies focusing on T cell biology, infectious diseases, autoimmunity, and cancer immunology.By unlocking insights into TCR expression patterns and dynamics, researchers can deepen their understanding of immune responses and potentially uncover novel therapeutic targets for a range of diseases. The Mouse TCR Monoclonal Antibody (AF488-conjugated, H57-597/HB218) represents a powerful asset for advancing scientific discoveries in the field of immunology and beyond.
Genie Fluor 488 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.