Mouse SF20 Recombinant Protein (RPPB0953)
- SKU:
- RPPB0953
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- SF20
- Synonyms:
- UPF0556 protein C19orf10 homolog
- Stromal cell-derived growth factor SF20
- Interleukin-25
- IL-25
- Source:
- Escherichia Coli
- Uniprot:
- Q9CPT4
Description
| Product Name: | Mouse SF20 Recombinant Protein |
| Product Code: | RPPB0953 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | SF20 |
| Synonyms: | UPF0556 protein C19orf10 homolog, Stromal cell-derived growth factor SF20, Interleukin-25, IL-25, D17Wsu104e, Il25, IL27, SF20, IL27w, R33729_1, C19orf10, Chromosome 19 Open Reading Frame 10. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Mouse SF20 was lyophilized from a 0.2µm filtered concentrated (1.0mg/ml) solution in PBS, pH 7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized Mouse SF20 in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Mouse SF20 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse SF20 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | MVSEPTTVPF DVRPGGVVHS FSQDVGPGNK FTCTFTYASQ GGTNEQWQMS LGTSEDSQHF TCTIWRPQGK SYLYFTQFKA ELRGAEIEYA MAYSKAAFER ESDVPLKSEE FEVTKTAVSH RPGAFKAELS KLVIVAKAAR SEL |
Mouse SF20 is a bone marrow stroma-derived growth factor. SF20 is expressed in the bone marrow, spleen stroma cells, resting mononuclear cells, resting CD8+ and CD19+ cells and activated CD8+ T cells. SF20 has been shown to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Among SF20’s biological activities is stimulation of the proliferation of FDCP2 cells (a mouse factor-dependent hemopoietic cell line) and mouse lymphoid cells.
Chromosome 19 Open Reading Frame 10 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids and having a molecular mass of 15.8kDa. The Mouse SF20 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MYDGF: was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Cellular Component: extracellular space; extracellular region Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; positive regulation of MAPKKK cascade; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; negative regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was identified in error as interleukin 25. This activity has not been reproducible, however, and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9CPT4 |
| NCBI GenInfo Identifier: | 61221740 |
| NCBI Gene ID: | 28106 |
| NCBI Accession: | Q9CPT4.1 |
| UniProt Secondary Accession: | Q9CPT4,Q3UG74, A2RSI7, |
| UniProt Related Accession: | Q9CPT4 |
| Molecular Weight: | 17,982 Da |
| NCBI Full Name: | UPF0556 protein C19orf10 homolog |
| NCBI Synonym Full Names: | DNA segment, Chr 17, Wayne State University 104, expressed |
| NCBI Official Symbol: | D17Wsu104e |
| NCBI Official Synonym Symbols: | Il25; Ly6elg |
| NCBI Protein Information: | UPF0556 protein C19orf10 homolog |
| UniProt Protein Name: | UPF0556 protein C19orf10 homolog |
| UniProt Synonym Protein Names: | Interleukin-25; IL-25; Stromal cell-derived growth factor SF20 |
| UniProt Gene Name: | D17Wsu104e |
| UniProt Entry Name: | CS010_MOUSE |
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