Mouse PDK4 Recombinant Protein (RPES0513)

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SKU:
RPES0513
Product type:
Recombinant Protein
Host species:
Baculovirus-Insect Cells
Reactivity:
Mouse
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Description

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Mouse PDK4 Recombinant Protein

Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an up-regulated gene in the heart and skeletal muscle of carnitine-deficient juvenile visceral steatosis (JVS) mice under fed conditions. PDK4 plays an important role in the inhibition of glucose oxidation via the phosphorylation of pyruvate dehydrogenase complex (PDC).PDK4 gene expression is stimulated by thyroid hormone (T(3)), glucocorticoids, and long chain fatty acids.

Product Name:Mouse PDK4 Recombinant Protein (RPES0513)
Product Code:RPES0513
Size:20µg
Species:Mouse
Expressed Host:Baculovirus-Insect Cells
Synonyms:AV005916
Accession:O70571
Sequence:Met1-Val412
Fusion tag:N-His-GST
Activity:Kinase activity untested
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the mouse PDK4 (O70571) (Met1-Val412) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Purity:> 85 % as determined by SDS-PAGE
Mol Mass:74.4 kDa
AP Mol Mass:65 kDa
Formulation:Supplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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